Reader Leah used the website's "Contact Me" to inquire whether "using vitamin B3 to prevent skin cancer" and "using vitamin C to protect skin" on 2022-6-10 is a traumatic science. I will discuss these two topics in two articles. I have already published six days ago that Vitamin B3 can prevent skin cancer?
Regarding the vitamin C part, reader Leah's question was:
"I have a fixed purchaser in the skin clinic in Northern California to recommend the non-cheap topical vitamin C (SkinCeuticals brand) as a skin antioxidant. However, I recently saw a British dermatologist who believes that these studies/suggestions exist in bias and conflict of interest, and I also want to teach topical ascorbic Is there sufficient certificate for the acid, or is it a professional salesperson? Thank you for your precious time to read this letter. I have been troubled for a long time and have never known what to ask for. I will only urge you to inquire. The science of skin care does not seem to be less than the science of health care students. ”External Vitamin C is called "Vitamin C Essence Liquid" in Taiwan. It has many brands (including SkinCeuticals) and a lot of ads.
For "A British dermatologist", reader Leah has attached two online links, and they are connected to two posts posted by Natalia Spierings on Instagram on May 28, 2022 (https://www.instagram.com/p/CeGLkF2Maze/, https://www.instagram.com/p/CeGLKRXJgsM/). These two posts are mainly based on the verdict of the efficacy of external vitamin C, because she believes that the relevant research is supported by the manufacturer or done by the manufacturer itself, which means that the player is suspected of being a referee. Dr.
Natalia Spierings specifically proposed SkinCeuticals and Dr. Sheldon Pinnell as examples. Dr. Sheldon Pinnell is a famous dermatologist and he is the founder of SkinCeuticals. He can also be said to be the inventor of external use of vitamin C. The first article about skin-on-skin vitamin C is the Topical vitamin C protects porcine skin from ultraviolet radiation-induced damage (topical vitamin C protects pig skin from damage caused by ultraviolet radiation).
Vitamin C (L-anti-Broken Blood Acid) is extremely unstable and difficult to penetrate the skin, so scientists have been looking for formulas that can overcome these two obstacles for more than 30 years. In poorly designed products, Vitamin C will oxidize and change color (yellow) in the bottle. Similarly, topical vitamin C may also oxidize on the skin surface, thereby causing free radicals and acidic byproducts or waste to accumulate on the skin. This will affect the skin barrier and may also interact with other skin care products, thereby accelerating skin aging. Please see these three 2017 articles below:
The Roles of Vitamin C in Skin Health. Normal skin contains high concentrations of vitamin C, which supports important and well-known functions such as stimulating gelatin synthesis and protecting the skin from ultraviolet light damage. This knowledge is usually why we need to develop external vitamin C. However, contrary to dietary vitamin C intake, we know very little about the efficacy of topical vitamin C.Enhancement of skin permeation of vitamin C using vibrating microneedles. Vitamin C is unstable when exposed to air, moisture, light, heat, metal ion, oxygen and swelling, and can then easily decompose into bioinert compounds such as 2,3-dione-L-guloconic acid, oxalic acid, L-suconic acid, L-xiconic acid or L-leic acid. Therefore, vitamin C has limited applications in various fields of cosmetics, skin diseases or medicines. This study aims to use vibrating microscope to increase the transdermal delivery of vitamin C.
Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. Clinical research on the efficacy of vitamin C topical agents remains limited, and the challenge is to find the most stable and penetrating agent for optimal results.
Therefore, although topical vitamin C cannot be considered a disease science itself, whether it has skin protection effects still lacks accurate scientific evidence. In other words, the voices in its advertising marketing must have exceeded the bottom line of real science.
Original text: Is Vitamin C Essence a Vicious Science